A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."
Jan 4, 2024
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B cell deficiency is a common condition that can result either from immunosuppressant drugs used to treat autoimmune disease or certain cancers—such as rituximab (RTX)—or from natural immune deficiency. These patients ...
Dec 18, 2023
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Researchers at the National Institutes of Health have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, ...
Dec 18, 2023
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The immune system can carry out many biological processes, from killing viruses to fighting cancer, thanks in large part to approximately 100 key cell-signaling proteins called cytokines, which instruct immune cells what ...
Dec 7, 2023
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Drug development for lung diseases is complicated. Most clinical trials that test novel drugs fail due to the fact that laboratory models cannot accurately replicate human physiology.
Dec 6, 2023
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The evolution of higher cognitive functions in human beings has so far mostly been linked to the expansion of the neocortex—a region of the brain that is responsible, inter alia, for conscious thought, movement and sensory ...
Nov 29, 2023
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Researchers at the RUDN Laboratory of Biology of Single Cells have studied the possibilities of DNA sequencing at the level of individual cells in patients with a rare form of childhood leukemia. The study revealed the mechanisms ...
Nov 29, 2023
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A team at Weill Cornell Medicine has mapped the location and spatial features of blood-forming cells within human bone marrow. Their findings confirm hypotheses about the anatomy of this tissue and provide a powerful new ...
Nov 14, 2023
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New research from Yale University has unveiled the complex cellular communication system that allows immune cells to mount responses to infection and cancer. The study, published in Nature Methods, reveals how different cells ...
Nov 8, 2023
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The journal Science has published a series of review articles regarding the outsized role that the hypothalamus plays in human behavior—regulating hunger pangs, sleep cycles and social interactions, the almond-sized brain ...
