Immunology

Towards more effective treatments for immunocompromised patients

For severely immunocompromised patients, a bone marrow transplant restores immune defenses and allows them to resume normal life. But after observing the nasopharyngeal system, where the body's first line of immune defense ...

Diseases, Conditions, Syndromes

New strategy for COVID-19 prophylaxis

SARS-CoV-2 viruses can hide from recognition by the immune system. However, the antiviral immune receptor RIG-I can be stimulated, which improves protection against lethal SARS-CoV-2 infections. Researchers led by Prof. Dr. ...

Diseases, Conditions, Syndromes

SARS-CoV-2 disrupts timing of immune response

Once an infection is under control, the body normally uses a biochemical messenger known as TGFβ to downgrade its immune response. In severe COVID-19, however, this messenger is released at the very beginning of the infection, ...

Immunology

The PANoptosome: A new frontier in innate immune responses

St. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and launch a multi-faceted innate immune response to infections with live viruses and bacteria. The discovery ...

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