Immunology

Immune system 'double agent' could be new ally in cancer fight

St. Jude Children's Research Hospital scientists have discovered that an enzyme called TAK1 functions like a "double agent" in the innate immune response, serving as an unexpected regulator of inflammation and cell death. ...

Immunology

Immune signature predicts asthma susceptibility

Asthma is a chronic inflammatory disease driven by the interplay of genetics, environmental factors and a diverse cast of immune cells. In their latest study, researchers at La Jolla Institute for Allergy and Immunology (LJI) ...

Immunology

Stem cell-derived intestine model mimics innate immune responses

A stem cell-derived in vitro model displays key small intestine characteristics including innate immune responses, according to a study published November 29, 2017 in the open-access journal PLOS ONE by Ying Chen and David ...

Diseases, Conditions, Syndromes

Can bats help humans survive the next pandemic?

In 2003, severe acute respiratory syndrome (SARS) infected a total of 8,098 people worldwide. First reported in China, it spread rapidly through more than two dozen countries in North America, South America, Europe and Asia.

Inflammatory disorders

Hibernating control cells or why inflammations become chronic

Rheumatoid arthritis is the most common autoimmune disease of the joints. It causes a chronic inflammatory response, with the body's own immune cells attacking the joint, including the cartilage and bone. This process does ...

Immunology

Clues about immune resolution identified in blood

Stopping a wound from bleeding is essential for human health. Blood coagulation - in which blood goes from liquid to gel and forms a clot - can prevent excessive bleeding and infection. But exactly what molecular events transpire ...

Immunology

How the human body first fights off pathogens

People constantly encounter viruses, bacteria or parasites. Fortunately, our skin, the specialized lining of our guts and other parts of our body that are exposed to the outside world prevent them from entering. When a pathogen ...

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