Diseases, Conditions, Syndromes

Severe COVID-19 may lead to long-term innate immune system changes

Severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, according to a small study. These changes may help explain why the disease can damage so many different ...

Immunology

Researchers uncover a cellular process that leads to inflammation

Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body's important inflammatory responses. Their findings, published in the journal Science Immunology, open ...

Genetics

New tool uncovers COVID-19 susceptibility mechanism

Researchers have discovered a mechanism for COVID-19 susceptibility using a newly created tool. The tool, GASPACHO, captures dynamic changes in gene expression along the innate immune response, allowing researchers to identify ...

Immunology

Understanding immunological memory

Humans encounter innumerable pathogenic bacteria, viruses and other microbes in their day-to-day activities. While infections from some pathogens can be easily cleared by the innate immune system, others can evade this first ...

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