Oncology & Cancer
Mitochondria come together to kill cancer cells
Targeting a pathway that controls the movement of mitochondria, the powerhouses of all cells, could reduce cancer invasiveness and resistance to radiotherapy.
Sep 12, 2018
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News tagged with integrin
Oncology & Cancer
Researchers review the role of integrins in human hepatocellular carcinoma
Globally, human hepatocellular carcinoma (HCC) is the sixth most common cancer and the fourth leading cause of cancer-related mortality. The worldwide incidences of HCC have been on the rise in recent decades. Unfortunately, ...
May 10, 2023
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Oncology & Cancer
New mechanism discovered that regulates the spread of breast cancer
A research group at the University of Turku, Finland, has discovered a completely new mechanism that cells use to circulate integrins on the cell surface. Aggressive breast cancer cells exploit this mechanism to spread and ...
Oct 18, 2021
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HIV & AIDS
Treatment with anti-α4β7 monoclonal antibody efficiently reduces transmission of SIV
A research group led by Prof. Li Guohui from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS), in collaboration with Prof. Chen Jianfeng's group from Shanghai Institute of Biochemistry ...
Jul 20, 2021
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Genetics
Study homes in on possible cause of sudden cardiac deaths
By studying the sick hearts removed from four patients undergoing heart transplants, researchers have identified a protein and a signaling pathway that may contribute to sudden death in an inherited form of heart disease.
Mar 3, 2020
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Medical research
Team tracks integrin's role in lung function
Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at Vanderbilt University Medical Center have discovered.
Feb 7, 2020
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Oncology & Cancer
New breast cancer stem cell clues may help develop therapeutics
Researchers have identified a new regulatory pathway that may play an important role in basal-like breast cancer (BLBC), a particularly aggressive form of breast cancer often referred to as "triple negative." This pathway ...
Nov 5, 2015
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Oncology & Cancer
Researchers discover new information on the spread of cancer
A new study from the University of Turku, Finland, shows that intracellular receptor signalling sustains cancer cells that have detached from the surrounding tissue. When the signalling is prevented, the cells cannot spread ...
Oct 8, 2015
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Oncology & Cancer
Integrin cell adhesion receptors are risky cancer drug targets
A possible cancer treatment strategy might in fact lead to increased metastasis in some cases. This finding from a team of LACDR researchers led by Erik Danen made the cover of the February 11 edition of Science Signaling.
Feb 11, 2014
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