Clearing a major hurdle in the field of microbiome research, Harvard Medical School scientists have designed and successfully used a method to tease out cause-and-effect relationships between gut bacteria and disease.
Dec 6, 2017
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The lining or epithelium of the gut is one of the body's most diverse and dynamic tissues, an ecosystem of cells that acts as one of the body's main interfaces with the outside world. To better understand this complex tissues ...
Nov 8, 2017
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Genes that regulate a cellular recycling system called autophagy are commonly mutated in Crohn's disease patients, though the link between biological housekeeping and inflammatory bowel disease remained a mystery. Now, researchers ...
Jul 27, 2017
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A Massachusetts General Hospital (MGH) research team has found how a variant in an important epigenetic enzyme—previously associated by population-based genetic studies with Crohn's disease and other immune disorders—interferes ...
Mar 3, 2017
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The natural life cycle of cells that line the intestine is critical to preserving stable conditions in the gut, according to new research led by a Weill Cornell Medicine investigator. The findings may lead to the development ...
Mar 1, 2017
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Numerous human diseases, including inflammatory bowel disease, diabetes and autism spectrum disorders have been linked to abnormal gut microbial communities, or microbiomes, but an open question is whether these altered microbiomes ...
Feb 16, 2017
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A study in mice shows that eating cruciferous vegetables—including broccoli, kale and cauliflower - helps the immune system to fight intestinal pathogens. The research might have implications for people with inflammatory ...
Feb 2, 2017
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Could inflammatory bowel disease and colon cancer be prevented by changing the shape of a single protein?
Jan 27, 2017
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Intestinal stem cells are among the most rapidly dividing cells in the body, busily creating new cells to replace the ones that are constantly being sloughed off. But unlike stem cells elsewhere in the body, those in the ...
Jun 2, 2016
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Researchers have identified a common variant in a non-coding RNA that may contribute to the intestinal inflammation that occurs in people with celiac disease. The findings point to a possible new risk factor for developing ...
Mar 31, 2016
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