The intestinal epithelium is the inner layer of the intestinal wall, which separates host tissue from the intestinal microbiota. This layer of cells plays a crucial role in water, electrolyte and nutrient absorption, while ...
Jun 8, 2020
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Researchers at the University of Helsinki have discovered how regenerative capacity of intestinal epithelium declines when we age. Targeting of an enzyme that inhibits stem cell maintaining signaling rejuvenates the regenerative ...
Jul 10, 2019
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Throughout the gastrointestinal tract there are specialized hormone-producing cells called enteroendocrine cells and, although they comprise only a small population of the total cells, they are one of the most important moderators ...
Jun 27, 2019
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The survival and fitness of multicellular organisms is tightly associated with their capacity to renew their tissues. This is particularly important for tissues that are permanently exposed to and challenged by the external ...
Jun 4, 2019
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Flies eating a Spartan diet are protected from leaky gut and the systemic inflammation associated with it as they age. Conversely, flies on a rich Atkins-like diet are more prone to developing intestinal permeability, a condition ...
Nov 5, 2018
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The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. The c-MYC transcription factor controls the activity of a large number of genes involved in cell division, and its ...
Sep 5, 2018
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Researchers at the University of Zurich have discovered the identity of the stem-cell niche of the colon. The niche comprises special cells that activate the stem cells of the adjacent intestinal epithelium and are responsible ...
Jun 6, 2018
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A new Johns Hopkins study of mice with the rodent equivalent of metabolic syndrome has added to evidence that the intestinal microbiome—a "garden" of bacterial, viral and fungal genes—plays a substantial role in the development ...
Feb 12, 2018
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Researchers at Baylor College of Medicine, Johns Hopkins University School of Medicine and the University of California, San Francisco have gained new insights into how the small intestine, one of the fastest renewing tissues ...
Jan 25, 2018
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The lining of the intestines - the epithelium - does more than absorb nutrients from your lunch. It grows, shrinks, and adjusts the very makeup of its cells in response to whatever you just ate. And understanding that process ...
Nov 27, 2017
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