Medical research

Solving chronic pain during intercourse

Women suffering from chronic conditions that result in painful intercourse represent about 10% of females of reproductive age—triggering a combined economic burden of more than $7.7 billion per year—yet scant knowledge ...

Medical research

An unconventional ion channel

Scientists at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified the first mechanosensitive ion channel to be found in an intracellular vesicle system. It responds to concentration changes within the vesicle, ...

Cardiology

How is the heartbeat regulated?

The heart can stably maintain blood flow—at rest or under stress—over a lifetime. Using a mouse model, an LMU team has now uncovered the role played by a specific class of ion channels in controlling the heart rate.

Neuroscience

New mechanism affecting nerve impulses discovered

Researchers at Linköping University, Sweden, have discovered a new mechanism by which substances can open a certain type of ion channel and thereby regulate nerve impulses. The study, published in the scientific journal ...

Neuroscience

New perspectives to treat neuropsychiatric diseases

Researchers at the Institute of Biology, Eötvös Loránd University (ELTE), Budapest, Hungary, studied the major types of neurons of the prefrontal cortex of the brain in an international collaboration. The research team ...

Genetics

Cardiac arrhythmias linked to gene mutations

Life-threatening cardiac arrhythmias can be linked to the functional and structural consequences of gene mutations. The study is published in the peer-reviewed journal Bioelectricity.

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Ion channel

Ion channels are pore-forming proteins that help establish and control the small voltage gradient across the plasma membrane of all living cells (see cell potential) by allowing the flow of ions down their electrochemical gradient. They are present in the membranes that surround all biological cells. The study of ion channels is known as channelomics and involves many scientific techniques such as voltage clamp electrophysiology (in particular patch clamp), immunohistochemistry, and RT-PCR.

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