The severity of immune-mediated intestinal diseases such as graft-versus-host disease (GVHD) or inflammatory bowel diseases is known to be associated with alterations in the gut microbiome, but what leads to such disruption ...
Feb 2, 2023
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Adipose tissue, commonly called "body fat," stores excess fatty acids and supplies it back when the need arises. Finely balanced iron levels are important for the health of adipocytes, the cells that make up adipose tissue. ...
Oct 5, 2018
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Researchers from Germans Trias i Pujol Research Institute (IGTP) have discovered that administering human apotransferrin to mice models affected by intracerebral hemorrhage can mitigate the damaging effects of this severe ...
Nov 21, 2023
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Northwestern Medicine scientists have identified a novel pathway that regulates cellular iron, which could lead to new therapies for patients with either an overload or deficiency of iron.
Mar 31, 2017
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Iron accumulation in myocardial cells, potentially resulting in heart failure or fatal arrhythmia, is one of the complications most feared by patients with thalassemia major, a hereditary disease also known as Mediterranean ...
Dec 7, 2016
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Researchers at Moffitt Cancer Center and colleagues have discovered that changes in the physical characteristics of the effector memory regulatory T cell can predict the progression risk of myelodysplastic syndromes (MDS) ...
Sep 13, 2012
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Hepatitis C virus (HCV) infects more than 170 million people worldwide. Approximately 80 percent of infections lead to chronic illness including fibrosis, cirrhosis, cancer and also hepatic iron overload. A new study completed ...
Jun 10, 2013
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Researchers at Moffitt Cancer Center and colleagues at six other institutions have recently tested a treatment for patients with myelodysplastic syndrome, or MDS, a blood-related malignancy that involves the ineffective production ...
Jun 22, 2012
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(HealthDay)—Exjade (deferasirox) has been approved by the U.S. Food and Drug Administration to remove excess iron in the blood among people with a genetic blood disorder called non-transfusion-dependent thalassemia (NTDT).
Jan 24, 2013
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New research suggests that synthetic peptides called minihepcidins may potentially treat two serious genetic blood diseases in children and adults. Although those diseases, beta-thalassemia and polycythemia vera, have opposite ...
May 6, 2016
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