Vanderbilt researchers have discovered a unique pathway that initiates islet β cell inflammation—a hallmark of type 2 diabetes—putting them a step closer to developing targeted therapeutics for the disease that affects ...
Jan 13, 2021
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25
A new study from Karolinska Institutet and the Helmholtz Diabetes Research Center shows that primary cilia, hair-like protrusions on endothelial cells inside vessels, play an important role in the blood supply and delivery ...
Dec 4, 2020
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64
Type 1 diabetes, or T1D, results from the autoimmune destruction of the insulin-producing cells of the pancreas. People with T1D require exogenous insulin and suffer swings in the levels of glucose in the blood that impact ...
Oct 22, 2020
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A team of researchers affiliated with multiple institutions in the U.S. has successfully tested the idea of transplanting pancreatic islet cells under the skin to treat diabetes in test mice and monkeys. In their paper published ...
Pancreatic islet transplants, which revive insulin production to treat type 1 diabetes, only last an average of three years.
Aug 31, 2020
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74
A protein that's common throughout the body plays a key role in regulating glucose levels, says new research conducted in the Cell Signal Unit at the Okinawa Institute of Science and Technology Graduate University (OIST) ...
Aug 28, 2020
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The multicellular, 3-D structure of human pancreatic islets—the areas of the pancreas containing hormone-producing or endocrine cells—has presented challenges to researchers as they study and manipulate these cells' function, ...
Jul 31, 2020
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4
The University of Alabama at Birmingham and Southern Research have discovered a new drug candidate that offers a major advance in the treatment for diabetes.
Jul 28, 2020
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44
Scientists at Sanford Burnham Prebys Medical Discovery Institute have mapped for the first time the vast network of proteins that interact with proinsulin, the protein the body normally processes into insulin. The study, ...
May 27, 2020
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1
Immunologists at St. Jude Children's Research Hospital have created a database that identifies gene-regulatory mechanisms in immune cells that facilitate Type 1 diabetes. The findings were published today in Nature Immunology.
Mar 31, 2020
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