Diseases, Conditions, Syndromes

iGeorge syndrome kidney problems may be caused by missing gene

Loss of function of the CRKL gene causes kidney and urinary tract defects in people with DiGeorge syndrome, a multinational team of scientists led by Columbia University Medical Center (CUMC) has found.

Genetics

Kidney disease gene found to also have a protective mutation

African Americans have long been known to be at increased risk of kidney disease due to a dangerous genetic mutation that creates a hole in the kidney cells, but Vanderbilt University Medical Center (VUMC) researchers have ...

Medical research

Finding the best models for liver and kidney disease

In two separate studies, researchers at EPFL have carried out extensive tests to develop the best mouse models for studying kidney and liver diseases. The findings provide crucial insights into both conditions, and are expected ...

Oncology & Cancer

FDA approves personalized therapy for metastatic bladder cancer

(HealthDay)—The first personalized treatment for patients with metastatic bladder cancer and susceptible fibroblast growth factor receptor (FGFR) genetic alterations was granted accelerated approval by the U.S. Food and ...

Medical research

New study pinpoints why some injured kidneys do not heal

Cedars-Sinai investigators have discovered why some injured kidneys heal while others develop scarring that can lead to kidney failure. Their findings, detailed in a paper published in Science, could lead to the development ...

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