A team of researchers including Jens Hansen, Rachel Sealfon, Rajastree Menon, and colleagues of the Kidney Precision Medicine Project, built on an existing specific human kidney tissue atlas relevant to health care at single-cell ...
In June 2023, Uresa A. (who was 15 years old at the time) received CAR-T cells at Universitätsklinikum Erlangen. The treatment was the last resort to slow down systemic lupus erythematosus (SLE), which is a serious autoimmune ...
Jul 8, 2024
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A study, presented at the 61st ERA Congress, has uncovered a significant breakthrough in the diagnosis and monitoring of kidney diseases associated with nephrotic syndrome. The study is also published in the New England Journal ...
May 25, 2024
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The development of a new treatment strategy for bacterial infections and sepsis is being led by researchers at Lund University. In a study published in Nature Communications, the researchers demonstrate how they can neutralize ...
Jan 10, 2024
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With SARS-COV-2 infection rates rising again, you may be wondering if you should get a COVID-19 vaccine booster shot. Yale physicians have built a tool to help answer these questions.
Dec 19, 2023
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A clinical study on special diets at the University of Cologne shows promising results on the use of a ketogenic diet as a possible treatment for hereditary polycystic kidney disease (ADPKD). This disease causes about 10% ...
Nov 7, 2023
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Northwestern University researchers have developed the first electronic device for continuously monitoring the health of transplanted organs in real time.
Sep 7, 2023
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Analysis of data from more than 1 million Danish inpatients identifies nearly 4,000 drug pairings that are associated with more frequent dosage adjustments when prescribed together—potentially hinting at previously undiscovered ...
Sep 7, 2023
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Based on findings from a study published today in The Lancet Regional Health—Americas, researchers at Johns Hopkins Medicine and three collaborating medical institutions suggest that people living with the human immunodeficiency ...
Jul 24, 2023
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Fresh insights into a protein that causes damage in kidneys and hearts could open up new treatment options for chronic kidney disease, research shows.
May 31, 2023
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Renal function, in nephrology, is an indication of the state of the kidney and its role in renal physiology. Glomerular filtration rate (GFR) describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCr) is the volume of blood plasma that is cleared of creatinine per unit time and is a useful measure for approximating the GFR. Both GFR and CCr may be accurately calculated by comparative measurements of substances in the blood and urine, or estimated by formulas using just a blood test result (eGFR and eCCr).
The results of these tests are important in assessing the excretory function of the kidneys. For example, grading of chronic renal insufficiency and dosage of drugs that are primarily excreted via urine are based on GFR (or creatinine clearance).
It is commonly believed to be the amount of liquid filtered out of the blood that gets processed by the kidneys. Physiologically, these quantities (volumetric blood flow and mass removal) are only related loosely.
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