Researchers at Memorial Sloan Kettering Cancer Center, New York, have concluded their phase 2 trial of chemotherapy in combination with the drugs nivolumab, and regorafenib.
Kidney organoids provide a promising platform in vitro to model the mechanisms of kidney disease, however, they are limited by an existing lack of knowledge of their inherent functional protein expression. In a new report ...
Knowing whether a tumor might grow or spread to other parts of a patient's body could be key to survival—and now scientists are one step closer to unlocking the ability to predict just that.
Apr 13, 2023
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Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function. The disease affects more than 12 million people worldwide, ...
Jan 22, 2024
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A growing repertoire of cell and molecule-based immunotherapies is offering patients with indomitable cancers new hope by mobilizing their immune systems against tumor cells. An emerging class of such immunotherapeutics, ...
Aug 23, 2023
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While Wilms tumor—also known as nephroblastoma—is rare, it is the most prevalent childhood kidney cancer. Researchers at Children's Hospital Los Angeles have now pinpointed a disruption in early kidney progenitor cell ...
May 1, 2023
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The number of immune cells in and around kidney tumors, the amount of dead cancer tissue, and mutations to a tumor suppressor gene called PBRM1 form a biomarker signature that can predict—before treatment begins—how well ...
Apr 6, 2023
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A study from researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Cell Biology, details a previously unexplained type of cell death called disulfidptosis that could open the door for ...
Feb 6, 2023
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Among patients with kidney cancer, the activity of four specific genes in the cancer cells seems to be able to predict the risk of the tumor spreading and the patient's chances of survival. This is shown by researchers from ...
Oct 17, 2022
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How cancers metastasize remains poorly understood. The process begins when cancer cells break off from a tumor and invade blood and lymphatic vessels, the body's alleyways. But studying invasion—typically a microscopic ...
Oct 20, 2021
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