Medical research

New window into brain cell communication debuts

The Allen Institute today released its first—and the world's largest—dataset of electrical brain activity gathered using Neuropixels, a new high-resolution silicon probe that can read out activity from hundreds of neurons ...

Immunology

Delivering immunotherapy directly to brain tumors

A new study gives insight into how immunotherapies, treatments that help the body's immune system fight cancer, might one day be delivered directly to the brain in order to treat brain tumors.

Oncology & Cancer

Cracking the code of a brain cancer that keeps coming back

One of the most common brain cancers in children, Sonic Hedgehog (SHH) medulloblastoma, also is one of the more survivable for most kids. Unfortunately, for a subset of patients the cancer resists treatment and relapses with ...

Oncology & Cancer

Researchers probe microbiome-cancer treatment link

Cancer immunotherapies have given patients with particularly intractable cancers new hope, but not everyone benefits. One such immunotherapy, known as CAR T-cell therapy, works only in about a third of the people who take ...

Medical research

New study offers hope for people suffering from chronic pain

Persistent pain, particularly neuropathic pain (NP), is a major health problem triggered by damage to or malfunction of the nervous system or by chronic diseases such as diabetes and multiple sclerosis. NP is seen as a sizable ...

Medical research

Experimental treatment slows prion disease, extends life of mice

Scientists using an experimental treatment have slowed the progression of scrapie, a degenerative central nervous disease caused by prions, in laboratory mice and greatly extended the rodents' lives, according to a new report ...

Alzheimer's disease & dementia

'Crosstalk' between genes promotes brain inflammation in Alzheimer's

A new study by scientists at Massachusetts General Hospital (MGH) offers clues about how to prevent inflammation of brain tissue, which promotes Alzheimer's disease (AD). The findings of this study online now and appearing ...

Medications

One step closer to chronic pain relief

Sortilin, which is a protein expressed on the surface of nerve cells, plays a crucial role in pain development in laboratory mice—and in all likelihood in humans as well. This is the main conclusion of the study "Sortilin ...

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