Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a next-generation drug called Ciapavir (SBI-0953294) that is effective at reactivating dormant human immunodeficiency virus (HIV). The research, ...
Jun 23, 2020
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Scientists have long known that even in the face of antiretroviral therapy, some HIV virus remains in infected individuals forever, hiding in small reservoirs of cells of the immune system. When these individuals discontinue ...
Apr 30, 2020
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The ultimate impediment to a cure for HIV infection is the presence of latent, HIV-infected cells, which can reawaken and produce new virus when antiretroviral drug therapy is stopped. These latent, HIV-infected cells are ...
Jul 13, 2016
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Highly active anti-retroviral therapy (HAART) has helped millions survive the human immunodeficiency virus (HIV). Unfortunately, HIV has a built-in survival mechanism, creating reservoirs of latent, inactive virus that are ...
Jul 30, 2015
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An immunomodulatory drug called fingolimod, which is approved for the treatment of multiple sclerosis, blocks human immunodeficiency virus (HIV) infection and transmission in human immune cells, according to a study published ...
Aug 13, 2020
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Current HIV medications can effectively prevent the disease's progression, but the virus can lurk for a lifetime in the body.
Dec 1, 2015
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(Medical Xpress) -- A team of researchers led by the University of North Carolina School of Medicine has demonstrated that latency develops soon after infection and slows when antiretroviral therapy is given.
May 30, 2012
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(Medical Xpress) -- A new collection of compounds, called "bryologs" – derived from a tiny marine organism – activate hidden reservoirs of the virus that currently make the disease nearly impossible to eradicate.
Jul 17, 2012
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People living with HIV must take a combination of three or more different drugs every day for the rest of their lives. Unfortunately, by following this strict treatment plan, they can suffer from side effects ranging from ...
Aug 24, 2017
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After 35 years of rigorous research, there is still no cure for HIV. Current drugs can be used to halt the infection, but fall short of reaching hidden reserves of dormant virus that can lurk for life within infected white ...
Apr 24, 2018
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