Neuroscience

Researchers discover fundamental pathology behind ALS

A team led by scientists at St. Jude Children's Research Hospital and Mayo Clinic has identified a basic biological mechanism that kills neurons in amyotrophic lateral sclerosis (ALS) and in a related genetic disorder, frontotemporal ...

Neuroscience

Dynamic switch for FUS proteinopathy

NUS biologists have discovered that dynamics of the FUS protein plays a key role in FUS proteinopathy that causes certain neurological diseases.

Neuroscience

Creating music by thought alone

Neurologists have created a hands-free, thought-controlled musical instrument, which they've recently described in a report in Frontiers in Human Neuroscience. Researchers hope that this new instrument will help empower and ...

Alzheimer's disease & dementia

How much does dementia risk increase after traumatic brain injury?

Having a moderate or severe traumatic brain injury (TBI) in middle-age is associated with an increased risk for future dementia, according to a retrospective of study of more than 40,000 TBI patients published in PLOS Medicine ...

Diseases, Conditions, Syndromes

Man who inspired ice bucket challenge is back in hospital

The man who inspired people around the world to dump buckets of ice water over their heads to raise millions of dollars for Lou Gehrig's disease research is back in the hospital and is keeping his sense of humor.

Genetics

What percentage of ALS is genetic?

Up to 90 percent of people with amyotrophic lateral sclerosis (ALS) report that they have no family history of the disease. Now, new research has found approximately 17 percent of such ALS cases may be caused by a gene mutation, ...

Parkinson's & Movement disorders

Hi-res view of protein complex shows how it breaks up protein tangles

Misfolded proteins are the culprits behind amyotrophic lateral sclerosis (ALS), Alzheimer's disease, Parkinson's disease, and other neurodegenerative brain disorders. These distorted proteins are unable to perform their normal ...

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