Researchers have determined how the most common gene mutation in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) disrupts normal cell function, providing insight likely to advance efforts to develop ...
Aug 26, 2015
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Scientists from the Gladstone Institutes and the University of Michigan have identified a cellular mechanism that can be targeted to treat ALS. The researchers revealed that increasing levels of a certain key protein successfully ...
Jun 8, 2015
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Federal health advisers on Wednesday narrowly ruled against an experimental drug for the debilitating illness known as Lou Gehrig's disease, a potential setback for patient groups who have lobbied for the medication's approval.
Mar 31, 2022
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New research on the experimental drug NU-9, invented and developed by two Northwestern University scientists to treat ALS (amyotrophic lateral sclerosis), shows it is more effective than existing FDA-approved drugs for the ...
May 17, 2022
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Scientists at University of Florida (UF) Scripps Biomedical Research have developed a potential medicine for a leading cause of ALS and dementia that works by eliminating disease-causing segments of RNA. The compound restored ...
Nov 22, 2022
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Scientists using an experimental treatment have slowed the progression of scrapie, a degenerative central nervous disease caused by prions, in laboratory mice and greatly extended the rodents' lives, according to a new report ...
Aug 2, 2019
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In 2013, University at Buffalo researchers published a paper showing how slowing down protein synthesis can improve myelin production and repair in some demyelinating diseases, such as Charcot-Marie-Tooth disease, (CMT). ...
Apr 22, 2015
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The human genome contains over 4.5 million sequences of DNA called "transposable elements," virus-like entities that "jump" around and help regulate gene expression. They do this by binding transcription factors, which are ...
Aug 31, 2020
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The repurposing of FDA-approved drugs for alternative diseases is a faster way of bringing new treatments into the clinic. Researchers at Karolinska Institutet in Sweden have repurposed a cancer drug for treatment of neuroinflammatory ...
Jun 6, 2022
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An achievement by UCLA neuroscientists could lead to a better understanding of astrocytes, a type of cell in the brain that is thought to play a role in Lou Gehrig's disease, also called amyotrophic lateral sclerosis, or ...
Dec 9, 2016
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