Medical research

Scientists solve mystery of nerve disease genes

For several years, scientists have been pondering a question about a genetic disease called Charcot-Marie-Tooth (CMT) disease type 2D: how can different types of mutations, spread out across a gene, produce the same condition?

Neuroscience

ALS disease mechanism discovered

A mechanism for amyotrophic lateral sclerosis (ALS) development has been discovered at Umeå University, Sweden. The researchers report that proteins with a defect structure spread the deformation to other proteins. The discovery ...

Neuroscience

Stem cell-gene therapy shows promise in ALS safety trial

Cedars-Sinai investigators have developed an investigational therapy using support cells and a protective protein that can be delivered past the blood-brain barrier. This combined stem cell and gene therapy can potentially ...

Alzheimer's disease & dementia

How much does dementia risk increase after traumatic brain injury?

Having a moderate or severe traumatic brain injury (TBI) in middle-age is associated with an increased risk for future dementia, according to a retrospective of study of more than 40,000 TBI patients published in PLOS Medicine ...

Neuroscience

New technique helps uncover changes in ALS neurons

Northwestern Medicine scientists have discovered that some neurons affected by amyotrophic lateral sclerosis (ALS) display hypo-excitability, using a new method to measure electrical activity in cells, according to a study ...

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