Leukemia stem cells protect themselves against the immune defense by suppressing a target molecule for killer cells. This protective mechanism can be tricked with drugs. In the journal Nature, scientists from Basel, Tübingen ...
Jul 17, 2019
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A molecular process involved in the action of anti-leukemia drugs has been discovered at Université de Montréal's Institute for Research in Immunology and Cancer (IRIC). While calling into question a central tenet of oncology, ...
Jul 9, 2019
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Patients with chronic myeloid leukemia can be treated with tyrosine kinase inhibitors. While these effective drugs lead to deep remission and prolonged survival, primitive leukemia stem cells resist elimination during the ...
Jun 11, 2019
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In the veins, stem cells constantly mature and develop into blood cells that are necessary for the body to work properly. Now, researchers from the University of Copenhagen and EMBL in Heidelberg have discovered exactly how ...
Apr 8, 2019
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Most patients with chronic myelogenous leukemia can be treated with tyrosine kinase inhibitors. These drugs are highly effective and lead to deep remission and prolonged survival. Yet quiescent leukemic stem cells persist ...
Mar 21, 2019
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All stem cells can multiply, proliferate and differentiate. Because of these qualities, leukemic stem cells are the most malignant of all leukemic cells. Understanding how leukemic stem cells are regulated has become an important ...
Mar 12, 2019
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This week a team of scientists and physicians from the U.K. published news of a second HIV positive man, in London, who is in long-term (18-month) HIV remission after undergoing treatment for Hodgkins lymphoma. The unexpected ...
Mar 7, 2019
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Advances in rapid screening of leukemia cells for drug susceptibility and resistance are bringing scientists closer to patient-tailored treatment for acute myeloid leukemia (AML).
Dec 8, 2018
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Researchers from the Princess Máxima Center for Pediatric Oncology have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather, the location of DNA mutations is relevant. Using ...
Nov 29, 2018
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Clinical trial results published in the journal Nature Medicine show 91 percent response rate to the combination of venetoclax with azacitidine in older adults newly diagnosed with acute myeloid leukemia (AML). Of 33 patients ...
Nov 28, 2018
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