Oncology & Cancer

Researchers discover key to making cancer-killing peptides

Researchers from Aalto University have found the mechanism of action for cancer-cell-killing peptides. This breakthrough is expected to lead to better medication, in particular better treatments for leukemia, skin cancer, ...

Genetics

Weill Institute researchers uncover basic cell pathway

Although all cells in an organism have the same DNA, cells function differently based on the genes they express. While most studies of gene expression focus on activities in the cell's nucleus, a new Cornell study finds that ...

Diabetes

Diabetes: When circadian lipid rhythms go wrong

Like all living beings, human physiological processes are influenced by circadian rhythms. The disruption of our internal clocks due to an increasingly unbalanced lifestyle is directly linked to the explosion in cases of ...

Medical research

Lipid-modifying enzyme: New target for pan-viral therapeutics

Three different disease-causing viruses -- poliovirus, coxsackievirus, and hepatitis C -- rely on their unwilling host for the membrane platforms enriched in a specific lipid, phosphatidylinositol 4 phosphate (PI4P) on which ...

Oncology & Cancer

DGK-alpha helps cancer cells gain traction and mobilize

Metastasizing cancer cells often express integrins that provide better traction. A new study in The Journal of Cell Biology reveals how a lipid-converting enzyme helps the cells mobilize these integrins.

Medical research

New study shows a role for cholesterol in pain perception

When you stub your toe or bump your head, you know that rubbing the injury can lessen the ouch. But how? New research from the lab of Scott B. Hansen, Ph.D., shows how physical pressure on cells can reduce pain signals, while ...

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