Medical research

New statistical method eases data reproducibility crisis

A reproducibility crisis is ongoing in scientific research, where many studies may be difficult or impossible to replicate and thereby validate, especially when the study involves a very large sample size. For example, to ...

Neuroscience

Lipid epoxides target pain, inflammatory pathways in neurons

When modified using a process known as epoxidation, two naturally occurring lipids are converted into potent agents that target multiple cannabinoid receptors in neurons, interrupting pathways that promote pain and inflammation, ...

Medications

Type 2 diabetes: Drugs initially increase glucose production

Although SGLT-2 inhibitors are central to the treatment of diabetes, their exact mode of action was hitherto unknown. In a study conducted by a research group led by Peter Wolf, Martin Krssak and Michael Krebs from MedUni ...

Oncology & Cancer

Map shows how cancer cells spread through the body

The vast majority of cancer deaths are attributed to metastasis, or the spread of tumors from one organ to another. Determining if a cancer will metastasize has been all but impossible, but if it does, it becomes more difficult ...

Diabetes

How poor oral hygiene may result in metabolic syndrome

Periodontal or gum disease is known to be a significant risk factor of metabolic syndrome, a group of conditions increasing the risk for heart disease and diabetes. In a new study, researchers from Tokyo Medical and Dental ...

Psychology & Psychiatry

Early trauma influences metabolism across generations

People who live through traumatic experiences in childhood often suffer long-lasting consequences that affect their mental and physical health. But moreover, their children and grandchildren can also be impacted as well. ...

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