Drug shows promise for starving out cancer cells
Starving out tumor cells may be a promising therapy for treatment-resistant lung cancer, according to a new study published in Science Advances.
May 6, 2024
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Starving out tumor cells may be a promising therapy for treatment-resistant lung cancer, according to a new study published in Science Advances.
May 6, 2024
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Lung tumors called adenocarcinomas sometimes respond to initially effective treatments by transforming into a much more aggressive small cell lung cancer (SCLC) that spreads rapidly and has few options for treatment. Researchers ...
Feb 8, 2024
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Lung adenocarcinoma is the most common lung cancer and the cause of most cancer-related deaths in the United States. There are several ways lung adenocarcinoma can arise, one of which is a mutation in a protein called EGFR ...
Feb 7, 2024
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An international team of researchers has demonstrated that a combination of inhibitors may suppress tumor growth and prevent relapse in patients with certain cancers, including head and neck squamous cell carcinoma and lung ...
Sep 12, 2023
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A new research paper titled "Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells" has been published ...
Mar 29, 2023
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A team of experts from the University of Barcelona, the University of Zaragoza and Hospital Clínic de Barcelona has found a mechanism of recruitment for tumor-associated cells (cancer-associated fibroblasts or CAFs), which ...
Jan 31, 2023
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KRAS is one of the most frequently activated oncogenes in human cancers. While the role of KRAS mutation in tumorigenesis and tumor maintenance has been extensively studied, the relationship between KRAS and the tumor immune ...
Jan 20, 2023
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One of the main challenges in oncology is the development of drugs against KRAS oncogenes. These oncogenes—genes that cause cancer when mutated—are responsible for a quarter of all human cancers, including the three tumor ...
Sep 1, 2022
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Melbourne researchers have discovered that cancer and immune cells rely on the same energy sources from our body to thrive, which could trigger a fundamental rethink of treatment options for some lung cancer patients.
Jun 30, 2022
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Mount Sinai researchers have developed a novel method to identify aggressive early-stage lung cancers and target drugs known as aurora kinase inhibitors to tumors that are especially likely to respond to them. The findings, ...
Mar 24, 2022
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