Medical research

An elusive mechanism of wasting syndrome cachexia revealed

Researchers from the Department of Molecular Biology and Genetics at Koc University in Turkey and the Pole of Endocrinology, Diabetology and Nutrition, Institute of Experimental and Clinical Research at Université Catholique ...

Oncology & Cancer

Genetic clues reveal lung cancer's next move

Knowing whether a tumor might grow or spread to other parts of a patient's body could be key to survival—and now scientists are one step closer to unlocking the ability to predict just that.

Diseases, Conditions, Syndromes

AI helps diagnose post-COVID lung problems

A new computer-aided diagnostic tool developed by KAUST scientists could help overcome some of the challenges of monitoring lung health following viral infection.

Diseases, Conditions, Syndromes

New algorithm could provide early warning for asthma attacks

A University of Texas at Dallas researcher and his international colleagues have developed an algorithm that might one day provide early medical alerts about the onset of asthma attacks or other respiratory problems.

Oncology & Cancer

Using AI to trace the origins of metastatic cancer cells

A large team of cancer researchers affiliated with several institutions in China, working with a pair of colleagues in the U.S., has found that artificial intelligence applications can be used to trace the origins of metastatic ...

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Lung cancer

Lung cancer is a disease of uncontrolled cell growth in tissues of the lung. This growth may lead to metastasis, which is the invasion of adjacent tissue and infiltration beyond the lungs. The vast majority of primary lung cancers are carcinomas of the lung, derived from epithelial cells. Lung cancer, the most common cause of cancer-related death in men and the second most common in women (after breast cancer), is responsible for 1.3 million deaths worldwide annually. The most common symptoms are shortness of breath, coughing (including coughing up blood), and weight loss.

The main types of lung cancer are small cell lung carcinoma and non-small cell lung carcinoma. This distinction is important, because the treatment varies; non-small cell lung carcinoma (NSCLC) is sometimes treated with surgery, while small cell lung carcinoma (SCLC) usually responds better to chemotherapy and radiation. The most common cause of lung cancer is long-term exposure to tobacco smoke. The occurrence of lung cancer in nonsmokers, who account for as many as 15% of cases , is often attributed to a combination of genetic factors, radon gas, asbestos, and air pollution, including secondhand smoke.

Lung cancer may be seen on chest radiograph and computed tomography (CT scan). The diagnosis is confirmed with a biopsy. This is usually performed via bronchoscopy or CT-guided biopsy. Treatment and prognosis depend upon the histological type of cancer, the stage (degree of spread), and the patient's performance status. Possible treatments include surgery, chemotherapy, and radiotherapy. With treatment, the five-year survival rate is 14%.

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