Medications

Herbal supplement shows promise against lung cancer

Berberine, a natural compound found in plants such as barberry and goldenseal, suppresses the proliferation of lung cancer cells in the lab, new research shows. It also reduces airway inflammation and damage to healthy lung ...

Diseases, Conditions, Syndromes

Another deadly disease for smokers: Pulmonary fibrosis

(HealthDay)—Current and former smokers are at risk for a lung disease called pulmonary fibrosis, but many aren't aware of the threat, the Pulmonary Fibrosis Foundation says.

Oncology & Cancer

New bacterial therapy approach to treat lung cancer

Lung cancer is the deadliest cancer in the United States and around the world. Many of the currently available therapies have been ineffective, leaving patients with very few options. A promising new strategy to treat cancer ...

Oncology & Cancer

Lung cancer: It is about more than smoking

World Cancer Day is February 4 and that makes this the ideal time to talk about lung cancer and smoking. Internationally, lung cancer is the most common cause of cancer deaths and the World Health Organization estimates that ...

Oncology & Cancer

Researchers investigate cancer cluster in Alabama town

Fruithurst is your quintessential small town. Located in Cleburne County, Alabama—just five miles on the other side of the Georgia state line—only a few hundred people call it home.

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Lung cancer

Lung cancer is a disease of uncontrolled cell growth in tissues of the lung. This growth may lead to metastasis, which is the invasion of adjacent tissue and infiltration beyond the lungs. The vast majority of primary lung cancers are carcinomas of the lung, derived from epithelial cells. Lung cancer, the most common cause of cancer-related death in men and the second most common in women (after breast cancer), is responsible for 1.3 million deaths worldwide annually. The most common symptoms are shortness of breath, coughing (including coughing up blood), and weight loss.

The main types of lung cancer are small cell lung carcinoma and non-small cell lung carcinoma. This distinction is important, because the treatment varies; non-small cell lung carcinoma (NSCLC) is sometimes treated with surgery, while small cell lung carcinoma (SCLC) usually responds better to chemotherapy and radiation. The most common cause of lung cancer is long-term exposure to tobacco smoke. The occurrence of lung cancer in nonsmokers, who account for as many as 15% of cases , is often attributed to a combination of genetic factors, radon gas, asbestos, and air pollution, including secondhand smoke.

Lung cancer may be seen on chest radiograph and computed tomography (CT scan). The diagnosis is confirmed with a biopsy. This is usually performed via bronchoscopy or CT-guided biopsy. Treatment and prognosis depend upon the histological type of cancer, the stage (degree of spread), and the patient's performance status. Possible treatments include surgery, chemotherapy, and radiotherapy. With treatment, the five-year survival rate is 14%.

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