Immunology

Scientists discover how gene mutation triggers immune disease

Scientists discovered how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery—successfully fixing donated immune cells from a 16-year-old boy with an abnormally ...

Diseases, Conditions, Syndromes

Rituximab effective for lupus-associated cytopenia

(HealthDay)—Rituximab treatment seems effective for systemic lupus erythematosus (SLE)-associated immune cytopenias, with an overall initial response rate of 86 percent, according to a study published online Dec. 16 in ...

Alzheimer's disease & dementia

Rheumatic diseases associated with increased dementia risk

(HealthDay)—Patients with various rheumatic diseases have an increased risk of dementia, according to a study published online Dec. 15 in the International Journal of Rheumatic Diseases.

Immunology

Protein's role in lupus development

Northwestern Medicine scientists have demonstrated that the loss of a protein called Bim in macrophages—a type of immune cell—leads to the development of lupus-like disease in mice. The findings, published in the Journal ...

Alzheimer's disease & dementia

Lupus linked with increased risk of dementia

A new International Journal of Geriatric Psychiatry study indicates that the risk of dementia may be elevated in individuals with systemic lupus erythematosus (SLE), an autoimmune disease affecting a range of systems including ...

Arthritis & Rheumatism

Omega-3 and Omega-6 fatty acid intake may affect lupus outcomes

Higher intake of omega-3 fatty acids was associated with better sleep quality and a decrease in depressive symptoms in lupus patients, among other patient-reported outcomes, according to new research findings presented this ...

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