Immunology

Scientists discover how gene mutation triggers immune disease

Scientists discovered how a gene mutation affects T cell function to promote immune disorders and then tested a treatment based on the discovery—successfully fixing donated immune cells from a 16-year-old boy with an abnormally ...

Diseases, Conditions, Syndromes

Rituximab effective for lupus-associated cytopenia

(HealthDay)—Rituximab treatment seems effective for systemic lupus erythematosus (SLE)-associated immune cytopenias, with an overall initial response rate of 86 percent, according to a study published online Dec. 16 in ...

Alzheimer's disease & dementia

Rheumatic diseases associated with increased dementia risk

(HealthDay)—Patients with various rheumatic diseases have an increased risk of dementia, according to a study published online Dec. 15 in the International Journal of Rheumatic Diseases.

Diseases, Conditions, Syndromes

Findings could help reduce risk of calciphylaxis in renal disease

(HealthDay)—For patients with late-stage renal disease, the presence of lupus anticoagulant and combined thrombophilias are risk factors for the development of calciphylaxis, according to a study published online Dec. 13 ...

Immunology

Protein's role in lupus development

Northwestern Medicine scientists have demonstrated that the loss of a protein called Bim in macrophages—a type of immune cell—leads to the development of lupus-like disease in mice. The findings, published in the Journal ...

Arthritis & Rheumatism

Environmental factors may trigger lupus onset and progression

While genetics play a role in the development of Lupus, a systemic autoimmune disease that can attack any organ system in the human body, so do environmental triggers, such as particulates in air pollution and ultraviolet ...

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