Nine of twelve leukemia patients who received infusions of their own T cells after the cells had been genetically engineered to attack the patients' tumors responded to the therapy, which was pioneered by scientists in the ...
Dec 10, 2012
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Early findings from a small clinical trial provide evidence that a new cellular immunotherapy approach may be effective in treating metastatic solid tumors. In the trial, researchers from the National Institutes of Health ...
Jul 11, 2024
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People with chronic lymphocytic leukaemia (CLL) are essentially more prone to infections such as varicella, influenza or pneumococci due to the reduction in the number of antibodies that their condition causes. Researchers ...
Mar 19, 2014
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Ibrutinib was approved in 2014 for the treatment of certain adults with chronic lymphocytic leukaemia (CLL), particularly as second-line treatment. The therapeutic indication was expanded in 2016. The drug is now also approved ...
Oct 11, 2016
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Idelalisib (trade name Zydelig) has been available since September 2014 for patients with follicular lymphoma or chronic lymphocytic leukaemia (CLL). The German Institute for Quality and Efficiency in Health Care (IQWiG) ...
Jan 8, 2015
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How can our immune system defend us against aggressors so diverse such as viruses, parasites, fungi and tumours? The secret lies in the large number of clones of T and B lymphocytes, each of which expresses a particular specific ...
Jan 23, 2015
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A two-prong approach combining ibrutinib and rituximab (Rituxin®) to treat aggressive chronic lymphocytic leukemia (CLL) produced profound responses with minor side effects in a Phase 2 clinical trial at the University of ...
Dec 10, 2012
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Researchers of Sechenov University, together with colleagues from Russia and Austria, have summarized everything known about cells producing group E antibodies. These molecules are responsible for most of the allergic reactions, ...
Nov 26, 2019
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New findings by scientists at the University of Southampton could help to predict how people with the most common form of leukaemia will respond to chemotherapy. The findings will help doctors decide which type of treatment ...
Dec 19, 2017
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Hypertension and left ventricular hypertrophy (LVH) have emerged as significant risk factors for cardiovascular events and all-cause mortality. Inflammation and nutrition play critical roles in the development of hypertension ...
Nov 7, 2023
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