Targeted T-cells can seek out and destroy tumor cells that carry specific antigen markers. Two novel anti-tumor therapies that take advantage of this T-cell response are described in articles published in Human Gene Therapy, ...
Oct 25, 2012
0
0
Genetic abnormalities accrued by tumor cells lead to inappropriate production of proteins at the wrong time or place, or even the synthesis of unusual hybrid proteins not found in normal cells. Such abnormalities can serve ...
Mar 1, 2013
0
0
(HealthDay)—Nearly 14 million people in the United States, or one in 23, are now cancer survivors.
Sep 17, 2013
0
0
The loss of one copy of the miR15a/miR16-1 gene cluster promoted initiation and progression of multiple myeloma in mice.
Feb 20, 2020
0
0
Adolescents and young adults with acute leukemia have a survival advantage if they receive treatment at a pediatric cancer center versus an adult center, according to a new study.
Apr 18, 2018
0
4
Low blood levels of immune cells called lymphocytes, in combination with higher levels of inflammation on PET/CT scans, are indicators of active sarcoidosis—an inflammatory disease that attacks multiple organs, particularly ...
Feb 25, 2021
0
7
A combination of two targeted agents - one approved by the Food and Drug Administration and one undergoing testing - has demonstrated safety as well as encouraging signs of effectiveness in a phase 1 clinical trial in patients ...
Dec 5, 2016
0
2
Conventional dendritic cells (cDCs) are the immune system's patrol. They recognize foreign threats and trigger a defensive response, while restraining immune reactions against inappropriate targets like host proteins. They ...
Nov 30, 2012
0
0
A Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called "cold" tumors that are nearly devoid of immune cells—and therefore unresponsive to immunotherapy—can ...
Sep 10, 2021
0
15
Immunotherapy has been a major breakthrough in oncology, with registered drugs now approved for use in an increasing number of tumour types—but little is known about its safety for HIV-positive cancer patients. A study ...
Oct 20, 2018
0
0
