Medical research

Molecular doorstop could be key to new tuberculosis drugs

Tuberculosis, which infects roughly one quarter of the world's population and kills nearly two million people a year, is not only deadly but ancient: signs of the disease have been found in Egyptian mummies. Despite its age, ...

Diseases, Conditions, Syndromes

Assay can ID M. tuberculosis resistance mutations

(HealthDay)—An automated molecular assay can detect Mycobacterium tuberculosis with resistance to drugs directly from sputum specimens, according to a study published in the Sept. 14 issue of the New England Journal of ...

Diseases, Conditions, Syndromes

A genetic variation may increase tuberculosis susceptibility

Researchers have shown that a single nucleotide change in a gene that affects production of hepcidin—a peptide involved in inflammation, immunity, and control of iron levels—is associated with greater susceptibility to ...

Diseases, Conditions, Syndromes

TB bacteria evolve at alarming rate

Researchers from the Vavilov Institute of General Genetics of the Russian Academy of Sciences (VIGG) and the Moscow Institute of Physics and Technology (MIPT) have established a catalog of mutations in 319 virulence genes ...

Diseases, Conditions, Syndromes

A defence mechanism that can trap and kill TB bacteria

A natural mechanism by which our cells kill the bacterium responsible for tuberculosis (TB) has been discovered by scientists at the Francis Crick Institute, which could help in the battle against antibiotic-resistant bacteria.

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