Immunology

How bacteria kill host cells from the inside

A bacterial pathogen that typically multiplies outside of host cells can enter and induce the destruction of cells called macrophages, according to a study published June 20 in the open-access journal PLOS Pathogens by Anne-Béatrice ...

Immunology

Molecular clock influences immune cell responses

Scientists have recently recognized that cells of the same type can behave differently in response to stimulation. In a new study, Yale researchers have shown how these varied responses are due in part to a desynchronized ...

Immunology

Stopping inflammation from becoming chronic

An international research team led by Friedrich Schiller University in Jena has developed a highly sensitive cell model to study the complex effects – and side effects – of anti-inflammatory drugs, with the ultimate aim ...

Immunology

Scientists stumble upon a model to study a lethal complication

More and more hospitalized patients with sepsis are being diagnosed with a deadly complication characterized by high levels of inflammation. A team of Yale researchers has uncovered clues to the cause of this complication—which ...

Medical research

Researchers breathe new life into COPD research using mouse models

The airways and lungs are affected by a range of diseases, but while some have been well characterized and treated, others, such as chronic obstructive pulmonary disorder (COPD), are still somewhat of an enigma. This condition ...

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