News tagged with macrophages

Related topics: immune cells · immune system · white blood cells · immune response · cells

Drug targeting could aid immune diseases

A new technique that targets drugs to specific cells could lead to improved therapies for diseases caused by an overactive immune response. The approach could help people affected by conditions such as arthritis and inflammatory ...

Sep 25, 2017
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Understanding how omega-3 dampens inflammatory reactions

Omega-3 fatty acids, which we primarily get through eating fatty fish, have long been thought to be good for our health. Many dietary studies have suggested that high intake is associated with a reduced risk of various disorders. ...

Aug 23, 2017
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Macrophage

Macrophages (Greek: big eaters, from makros "large" + phagein "eat"; abbr. ) are white blood cells within tissues, produced by the division of monocytes. Human macrophages are about 21 micrometres in diameter. Monocytes and macrophages are phagocytes, acting in both non-specific defense (or innate immunity) as well as to help initiate specific defense mechanisms (or adaptive immunity) of vertebrate animals. Their role is to phagocytose (engulf and then digest) cellular debris and pathogens either as stationary or as mobile cells, and to stimulate lymphocytes and other immune cells to respond to the pathogen. They can be identified by specific expression of a number of proteins including CD14, CD11b, F4/80 (mice)/EMR1 (human), Lysozyme M, MAC-1/MAC-3 and CD68 by flow cytometry or immunohistochemical staining. They move by action of Amoeboid movement.

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