Smoke from more than 200 wildfires burning across Canada has been turning skies hazy in North American cities far from the flames.
May 23, 2023
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A structure surrounding ovarian cancer trains cells called macrophages to protect the tumor from immune attack, according to new research led by Queen Mary University of London.
May 16, 2023
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Macrophages, a type of white blood cell, defend the body by engulfing and digesting foreign particles, such as bacteria, viruses, and dead cells. The immune cells also tend to accumulate in solid tumors, so tracking them ...
May 8, 2023
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Pulmonary macrophages are a heterogeneous population of immune cells that patrol the lungs, ingesting particulates and microbes, and activating inflammation when necessary. During homeostasis, two main subsets of macrophages ...
May 5, 2023
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A treatment to prevent runaway inflammation in patients with severe COVID-19 is a step closer after a University of Queensland-led study into how immune cells respond to the virus.
May 3, 2023
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Researchers at the Icahn School of Medicine at Mount Sinai have demonstrated in a preclinical study a potential new therapeutic approach to treating the most common form of lung cancer.
Apr 20, 2023
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A team from the Nagoya University Graduate School of Medicine in Japan has uncovered new information about how microglia, the resident immune cells in the brain, colonize the brain during the embryonic stage of development. ...
Apr 12, 2023
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Muscle is able to regenerate through a process that involves multiple steps and players, including the immune system. As our organism ages, the muscles lose the capacity to regenerate.
Mar 23, 2023
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Most immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer. Targeting a different type of immune cell called macrophages could be a more effective approach, ...
Mar 16, 2023
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A study conducted by researchers at the University of Liège on group 2 innate lymphoid cells (or ILC2s) shows that the functional reprogramming of these cells following their exposure to viruses allows our body to react ...
Feb 24, 2023
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Macrophages (Greek: big eaters, from makros "large" + phagein "eat"; abbr. MΦ) are white blood cells within tissues, produced by the division of monocytes. Human macrophages are about 21 micrometres in diameter. Monocytes and macrophages are phagocytes, acting in both non-specific defense (or innate immunity) as well as to help initiate specific defense mechanisms (or adaptive immunity) of vertebrate animals. Their role is to phagocytose (engulf and then digest) cellular debris and pathogens either as stationary or as mobile cells, and to stimulate lymphocytes and other immune cells to respond to the pathogen. They can be identified by specific expression of a number of proteins including CD14, CD11b, F4/80 (mice)/EMR1 (human), Lysozyme M, MAC-1/MAC-3 and CD68 by flow cytometry or immunohistochemical staining. They move by action of Amoeboid movement.
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