Glioblastoma multiforme (GBM) is the most common of all malignant brain tumors that originate in the brain. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant ...
Feb 1, 2012
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Malignant melanoma is a highly aggressive and notoriously chemoresistant form of cancer. In a new paper, Ohanna et al. reveal that anti-melanoma drugs may, paradoxically, induce a senescence-associated secretory profile ("secretome") ...
Jun 6, 2011
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Glioblastoma multiforme (GBM) is the most common malignant brain cancer in humans. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant to current therapies. ...
Nov 14, 2011
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Growth hormone has been identified as playing a key role in reducing inflammation and increasing survival rates following liver surgery.
May 5, 2020
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A molecule that helps cancer cells evade programmed self-destruction, an internal source of death, might also help malignant cells hide from the immune system, an external source of death.
Oct 7, 2014
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In a world first, Newcastle researchers have discovered the mechanisms acute myeloid leukemia (AML) cells use to produce "free radicals"—the byproduct of a cell process that aggressively fuels the growth of cancer cells ...
Mar 29, 2023
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A study from The Wistar Institute demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of stem-like chemoresistant cells following cisplatin treatment. Researchers showed that a combination ...
Dec 20, 2019
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A research paper published in Nature Cancer details new insights into the role of efferocytosis—the burying of dead cells—in pancreatic cancer that spreads to the liver.
Feb 14, 2024
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Knocking out a single enzyme dramatically cripples the ability of aggressive cancer cells to spread and grow tumors, offering a promising new target in the development of cancer treatments, according to a new study by researchers ...
Aug 26, 2013
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Only one in 100,000 people suffer from a pheochromocytoma, a tumor of the adrenal gland. If the tumor has already metastasized, a radioactive compound can be used to detect malignant cells that have spread to other parts ...
Feb 9, 2023
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