Why mosquito-borne dengue virus causes more severe disease in some individuals, including hemorrhagic fever with or without shock, remains controversial and researchers are focusing on the factors related to the interaction ...
Jun 12, 2017
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Mast cells, a type of white blood cell, are present in the airways of severe asthmatics even in the face of aggressive treatment, and their presence is associated with key indicators of severe asthma. It has long been thought ...
May 17, 2017
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Allergies are the commonest cause of asthma. The immune system over-reacts to harmless substances such as birch or grass pollen, for example, forming immunoglobulin E antibodies (IgE). Together with the inflammatory cells ...
Mar 3, 2017
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Systemic mastocytosis is a rare, incurable disease that affects approximately one in 10,000 people. It is a haematological tumour disease, similar to leukaemia, in which the bone marrow and other organs, such as the bowel, ...
Dec 13, 2016
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When NK cells encounter cancer or virally infected cells, they adhere to them and quickly congregate their destructive granules on the area of contact with the diseased cell. The granules, which contain molecules that can ...
Dec 5, 2016
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Researchers in France have identified a molecular motor that controls the release of inflammatory factors that cause severe and fatal allergic reactions. The study, "Kinesin-1 controls mast cell degranulation and anaphylaxis ...
Oct 24, 2016
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The hair-of-the-dog-that-bit-you is a time-honored allergy remedy for a good reason: It works.
Sep 26, 2016
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A study led by University of Cincinnati (UC) lipid metabolism researchers lends additional insight into how bacteria in the gut, or lack thereof, influences intestinal mast cells (MMC) activation and perhaps fat absorption. ...
Sep 8, 2016
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A global trial of an oral medication called midostaurin indicates that the drug can produce partial or complete resolution of organ damage in 60 percent of patients with a group of rare blood cancers known collectively as ...
Jun 29, 2016
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Simultaneous pre-treatment with antihistamines that block both the H1 and H4 antihistamine receptors suppressed the gastrointestinal symptoms of food allergy in mice, according to researchers at National Jewish Health. The ...
May 25, 2016
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