Oncology & Cancer

Research sheds new light on pancreatic cancer metastasis

With an overall survival rate of 9% for those diagnosed, pancreatic cancer remains exceedingly difficult to treat. However, the patient's primary tumor typically isn't what leads to death—it is the cancer's ability to evade ...

Oncology & Cancer

Big data analysis finds cancer's key vulnerabilities

Thousands of different genetic mutations have been implicated in cancer, but a new analysis of almost 10,000 patients found that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes and that, ...

Oncology & Cancer

Targeting the engine room of the cancer cell

Researchers at Columbia University Irving Medical Center (CUIMC) have developed a highly innovative computational framework that can support personalized cancer treatment by matching individual tumors with the drugs or drug ...

Cardiology

Mending broken hearts with cardiomyocyte molds

2.5 billion. That's approximately the number of times the human heart beats in 70 years. And sometimes during the course of its unrelenting contractions and relaxations, the heart muscle can no longer bear the strain.

Medical research

Our muscles measure the time of day

Biological clocks throughout the body trigger the release of the hormone melatonin during sleep, induce the secretion of digestive enzymes at lunchtime or keep us awake at the busiest moments of the day. A "master clock" ...

Medical research

Scientists find key cues to regulate bone-building cells

The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic as University of Wisconsin-Madison scientists have identified two proteins found in bone marrow as key regulators of the master cells ...

Oncology & Cancer

'Master switch' helps cancer cells survive stress

Scientists have discovered a 'master switch' within cancer cells that seems to override the normal stress response and allows them to survive conditions that would normally be lethal.

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