A new research perspective was published in Oncotarget. The paper is titled "WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?"
Feb 27, 2023
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An enzyme that drives the growth of an often-lethal childhood brain cancer may hold the key to a future treatment, says a McMaster University-led study.
Nov 10, 2022
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An international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expression is tightly correlated with the response to chemotherapy in medulloblastomas, ...
Nov 8, 2022
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A deep dive into the proteins and protein activities of human tumors grown in mouse models expands the potential therapeutic pathways to treat medulloblastoma, according to a new study published in the Journal of Proteome ...
Sep 27, 2022
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It may soon be possible to identify Group 4 medulloblastomas—the most common malignant brain tumor in children—from more aggressive Group 3 tumors. Research based on a little-explored part of RNA, which creates proteins, ...
Sep 21, 2022
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An aggressive type of pediatric brain tumor, medulloblastoma, exists in a pre-malignant form at birth after initially developing during the first or second trimester of pregnancy, according to a new international study. As ...
Sep 21, 2022
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When MUSC Hollings Cancer Center researcher Jezabel R. Blanco, Ph.D., began studying neurosciences, first as a graduate student and later as a postdoctoral fellow, her research was focused on understanding the mechanisms ...
Jul 21, 2022
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Effective and safe treatments are needed for medulloblastoma—the most common type of cancerous brain tumor in children—especially for patients whose cancer has spread to the spinal cord. A recent phase I clinical trial ...
Jul 14, 2022
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Scientists at St. Jude Children's Research Hospital have identified how an appendage on the surface of cells, called the primary cilium, contributes to certain types of medulloblastoma. The study has implications for drug ...
Jul 8, 2022
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UNC Lineberger Comprehensive Cancer Center researchers have demonstrated that a novel combination of two drugs that act as targeted inhibitors, delivered in a nanoparticle formulation, extend the survival of mice with medulloblastoma. ...
Jan 26, 2022
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