The mutation occurs in the androgen-synthesizing enzyme 3βHSD1 in castration-resistant prostate cancer (CRPC), according to research published online today in Cell. This mutation enables the tumor to make its own supply ...
Aug 29, 2013
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(Medical Xpress) -- The very first in the series of mutations causing colon cancer occurs in the beta-catenin gene; this gene is abnormally activated in about 90 percent of colorectal cancer patients, and in a much smaller ...
May 1, 2012
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Using a highly sensitive technology called NanoString, researchers have identified seven targets that could potentially be used to develop new immunotherapies for patients with metastatic melanoma, according to a study published ...
Sep 10, 2013
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Leptomeningeal disease is a rare but lethal complication faced by late-stage melanoma patients. It occurs when cancer cells spread to the membranes covering the brain and spinal cord, or the leptomeninges. This condition, ...
Jun 11, 2024
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A new study has found that the circadian clock—which synchronizes physiological and cellular activities with the day-night cycle and is generally thought to be tumor suppressive—in fact has a contextually variable role ...
Jan 24, 2024
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A study at The University of Texas MD Anderson Cancer Center showed that circulating tumor cells (CTCs), a form of liquid biopsy, was independently associated with melanoma relapse, suggesting CTC assessment may be useful ...
Feb 3, 2020
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(Medical Xpress)—The most devastating feature of cancer is that it often spreads throughout the human body and forms secondary tumors also known as metastases. One of the most aggressive metastatic cancers with no currently ...
Oct 30, 2013
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Metastatic melanoma is a highly aggressive skin cancer whose incidence is on the rise at an alarming rate. Research has revealed that metastatic tumor cells share similar signaling pathways with embryonic stem cells to sustain ...
Sep 15, 2014
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If melanoma spreads, there are various therapies that can be used. However, there is still insufficient research into who responds to which therapy and whether resistance may develop over time.
May 16, 2024
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An experimental drug aimed at restoring the immune system's ability to spot and attack cancer halted cancer progression or shrank tumors in patients with advanced melanoma, according to a multisite, early-phase clinical trial ...
Mar 4, 2014
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