Oncology & Cancer

Cancer: Unraveling a mechanism behind cellular proliferation

A hallmark of cancer is uncontrolled and sustained cell division. One particular overactive protein is implicated in this malfunction. EPFL scientists have discovered a complex mechanism that regulates this protein's activity ...

Medical research

Scientists find 3D structure of key drug target for diabetes

An international team led by scientists at The Scripps Research Institute (TSRI) has determined and analyzed the three-dimensional atomic structure of the human glucagon receptor. The receptor, found mainly on liver and kidney ...

Medical research

Researchers design variant of main painkiller receptor

Opioids, such as morphine, are still the most effective class of painkillers, but they come with unwanted side effects and can also be addictive and deadly at high doses. Designing new pain-killing drugs of this type involves ...

Medical research

Cholesterol sets off chaotic blood vessel growth

A study at the University of California, San Diego School of Medicine identified a protein that is responsible for regulating blood vessel growth by mediating the efficient removal of cholesterol from the cells. Unregulated ...

Medical research

Study uses Botox to find new wrinkle in brain communication

National Institutes of Health researchers used the popular anti-wrinkle agent Botox to discover a new and important role for a group of molecules that nerve cells use to quickly send messages. This novel role for the molecules, ...

Diabetes

Telmisartan reverses insulin resistance in mice

(HealthDay)—Treating mice fed a high-fat diet with telmisartan reverses insulin resistance and glucose intolerance, but only when the peroxisome proliferator-activated receptor-δ (PPAR-δ) gene is present, according to ...

Immunology

Cholesterol boosts the memory of the immune system

The memory of the human immune system is critical for the development of vaccines. Only if the body recognizes a pathogen with which it has already come into contact in the case of a second infection, the immune system can ...

page 5 from 7