Immunology

CRISPR screen identifies new anti-inflammatory drug target

A metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inflammatory therapeutics, Vanderbilt researchers have discovered. They report Nov. 11 in the ...

Overweight & Obesity

Hormonal changes at menopause up abdominal obesity

(HealthDay)—The increase in total body fat and abdominal fat seen at menopause is due to the hormonal changes taking place, which can be improved by estrogen treatment, according to a study published in the October issue ...

Medical research

Study shows promising safety results for anti-aging drug

The search for the fountain of youth led to a 2009 discovery that a drug called rapamycin was shown to extend the lifespan of mice. Since that time, studies on the metabolic side effects of rapamycin have made it unclear ...

Neuroscience

Obesity, metabolic factors linked to faster cognitive decline

People who are obese and also have high blood pressure and other risk factors called metabolic abnormalities may experience a faster decline in their cognitive skills over time than others, according to a study published ...

Genetics

New genes discovered for adult BMI levels

A large international study has identified three new gene variants associated with body mass index (BMI) levels in adults. The scientific consortium, numbering approximately 200 researchers, performed a meta-analysis of 46 ...

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