Cardiology
Metabolism switch signals end for healing hearts
Researchers have identified the process that shuts down the human heart's ability to heal itself, and are now searching for a drug to reverse it.
Sep 19, 2017
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141
News tagged with metabolic pathways
Diabetes
Single gene cause of insulin sensitivity may offer insight for treating diabetes
(Medical Xpress)—The first single gene cause of increased sensitivity to the hormone insulin has been discovered by a team of Oxford University researchers.
Sep 12, 2012
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Oncology & Cancer
How cancer cells get by on a starvation diet
Cancer cells usually live in an environment with limited supplies of the nutrients they need to proliferate — most notably, oxygen and glucose. However, they are still able to divide uncontrollably, producing new cancer ...
Nov 21, 2011
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1
Oncology & Cancer
Blocking telomerase kills cancer cells but provokes resistance, progression
Inhibiting telomerase, an enzyme that rescues malignant cells from destruction by extending the protective caps on the ends of chromosomes, kills tumor cells but also triggers resistance pathways that allow cancer to survive ...
Feb 21, 2012
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Health
Oat and rye bran fibres alter gut microbiota, reducing weight gain and hepatic inflammation
In a newly published experimental study, the consumption of dietary fiber from oat and rye brans supported the growth of beneficial gut microbiota, which in turn ameliorated cholesterol metabolism, enhanced gut barrier function ...
Jul 2, 2020
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5
Inflammatory disorders
Alterations in fatty acid synthesis linked to sepsis inflammation
Sepsis is a leading cause of death for patients in intensive care units. The excessive systemic inflammation in individuals with sepsis damages organs and can lead to death. Therapeutic options for sepsis are limited and ...
Jan 9, 2015
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9
Oncology & Cancer
Discovery offers potential for stripping tumors of T cell protection
Immunologists at St. Jude Children's Research Hospital have discovered that tumors use a unique mechanism to switch on regulatory T cells to protect themselves from attack by the immune system. Surprisingly, the mechanism ...
Feb 24, 2021
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187
Medical research
Inflammation controlled differently in brain and other tissues, study finds
A team led by scientists from The Scripps Research Institute has identified a new metabolic pathway for controlling brain inflammation, suggesting strategies for treating it.
Oct 20, 2011
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Oncology & Cancer
Cancer cells' plasticity makes them harder to stop
When metastatic cancer cells need to avoid a threat, they simply reprogram themselves. Rice University scientists are beginning to get a handle on how they survive hostile environments.
Feb 8, 2019
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57
Genetics
Mice reveal 38 new genes involved in hearing loss
Multiple new genes involved in hearing loss have been revealed in a large study of mouse mutants by researchers from the Wellcome Sanger Institute and King's College London, and colleagues. The new genes identified reveal ...
Apr 11, 2019
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