Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts ...
Jul 6, 2016
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Stating that sleep is an essential biological process seems as obvious as saying that the sun rises every morning. Yet, researchers' understanding of the molecular mechanisms underlying the effects of sleep loss is still ...
Feb 12, 2015
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A new study in women suggests that experiencing one or more stressful events the day before eating a single high-fat meal can slow the body's metabolism, potentially contributing to weight gain.
Jul 14, 2014
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The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Jan 13, 2013
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Researchers have found new evidence that metabolic stress can increase the onset of atrial arrhythmias, such as atrial fibrillation (AF), a common heart condition that causes an irregular and often abnormally fast heart rate. ...
Jan 8, 2013
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As part of their ongoing research investigating the biology of aging, the greatest risk factor for type 2 diabetes and other serious diseases, scientists at Joslin Diabetes Center have identified a new factor—microRNA processing ...
Sep 26, 2012
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Inflammation and cell stress play important roles in the death of insulin-secreting cells and are major factors in diabetes. Cell stress also plays a role in Wolfram syndrome, a rare, genetic disorder that afflicts children ...
Aug 7, 2012
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A molecule thought to limit cell proliferation also helps cancer cells survive during initial tumor formation and when the wayward cells spread to other organs in the body, researchers at the University of Illinois at Chicago ...
Jun 14, 2012
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A study conducted in mice has found that intermittent fasting brought benefits beyond weight loss, suggesting the practice could help the body better process glucose and reduce age-related declines in intestinal function. ...
Apr 8, 2024
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Diabetes is a global health burden. A whopping 536 million people worldwide struggle with diabetes. Diabetic cardiomyopathy (DC) is a serious condition characterized by impaired heart function due to diabetes-related metabolic ...
Apr 4, 2024
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