Oncology & Cancer

What reactivates dormant cancer cells?

Researchers at Columbia University have found a molecule that is responsible for arousing dormant cells from breast cancer and nudging them to create metastases. Silencing this molecule, called Malat1, in mice with breast ...

Oncology & Cancer

Immunotherapy for brain cancer metastases shows clinical benefit

In a phase 2 clinical trial of the immune checkpoint inhibitor pembrolizumab, investigators found that 42 percent of patients with metastatic brain cancer benefited from the therapy, with seven patients in the trial surviving ...

Oncology & Cancer

T-cell interactions vary between tumor microenvironments

A team led by Northwestern Medicine investigators has discovered differences in the distribution and interaction of T-cells within the microenvironment of different regions of both brain tumors and brain metastases, according ...

Oncology & Cancer

Scientists discover part of the origins of metastasis

Metastatic cells occur in many forms of cancer. They originate in primary tumors and then break away and migrate. They travel through the tissues surrounding them, through blood vessels or lymphatic channels. Along the way, ...

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