Memorial Sloan Kettering Cancer Center (MSK) molecular pharmacologist Daniel Heller, PhD, and colleagues have identified a new strategy to target drugs specifically to cancer sites, including metastatic tumors. The approach ...
Jul 6, 2016
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46
At any given moment, the human genome spells out thousands of genetic words telling our cells which proteins to make. Each word is read by a molecule known as a tRNA.
Jun 2, 2016
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56
Conventional chemotherapy generally fails to eradicate aggressive breast cancers due to the early distant metastasis that can occur in these diseases. Triple-negative breast cancer (TNBC) is a particularly aggressive subtype ...
May 12, 2016
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86
In a step toward more targeted treatments for cancer patients, UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center researchers have demonstrated how a genetic mutation drives the most common type of lymphoma ...
May 4, 2016
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54
Scientists at UC San Francisco have been able to directly observe, for the first time, how invasive cancer cells create a beachhead as they migrate to the lung in a mouse model of metastatic cancer. What they saw was utterly ...
Mar 17, 2016
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74
Two forms of a peptide derived from a naturally-occurring human protein can force tumors to shrink significantly in an animal model of metastatic ovarian cancer, according to a team led by researchers from Boston Children's ...
Mar 9, 2016
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317
Researchers at University of California, San Diego School of Medicine and Moores Cancer Center, with colleagues in Spain and Germany, have unraveled how elevated levels of particular proteins in cancer cells trigger hyperactivity ...
Feb 27, 2016
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91
When breast cancer becomes advanced and spreads to other organs, patient survival is drastically reduced, prompting the need to explore the genes that may cause tumor cells to metastasize.
Feb 12, 2016
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208
There's apparently safety in numbers, even for cancer cells. New research in mice suggests that cancer cells rarely form metastatic tumors on their own, preferring to travel in groups since collaboration seems to increase ...
Feb 1, 2016
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108
A doctor treating a patient with a potentially fatal metastatic breast tumor would be very pleased to find, after administering a round of treatment, that the primary tumor had undergone a change in character - from aggressive ...
Dec 22, 2015
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97
