Oncology & Cancer

ASCO: Trametinib improves survival in metastatic melanoma

(HealthDay) -- For patients with metastatic melanoma with activating mutations in serine-threonine protein kinase B-RAF (BRAF), treatment with the oral selective MEK inhibitor trametinib is associated with improved progression-free ...

Oncology & Cancer

New research opens the 'black box' of malignant melanoma

When malignant melanoma metastasizes to the brain, it is a death sentence for most patients. Metastatic melanoma is the deadliest of the skin cancers and the mechanisms that govern early metastatic growth and interactions ...

Oncology & Cancer

Immunity against melanoma is only skin deep

In a newly published study, researchers at Dartmouth's Norris Cotton Cancer Center find that unique immune cells, called resident memory T cells, do an outstanding job of preventing melanoma. The work began with the question ...

Oncology & Cancer

Cancer cells send out 'drones' to battle immune system from afar

Cancer cells are more than a lump of cells growing out of control; they participate in active combat with the immune system for their own survival. Being able to evade the immune system is a hallmark of cancer. Cancer cells ...

Medical research

Lung disease and melanoma: A common molecular mechanism?

A Yale-led team of researchers has solved a biological mystery about the common genesis of many serious diseases such as asthma and metastatic melanoma, identifying the first known pathway by which their cellular functions ...

Oncology & Cancer

New therapy wipes out cervical cancer in two women

Aricca Wallace knew she was nearly out of time. For more than three years, she had suffered cramping and irregular bleeding, which her doctor thought was a side effect of her birth control implant, known as an intrauterine ...

Oncology & Cancer

Turning the tables on cancer

In the spring of 2012, Tom Stutz was a man without a future. Just getting through the day took all of his energy and determination.

Oncology & Cancer

Scientists identify new approach for treating skin cancer

Using new and innovative immune-therapeutic approaches to silence "don't eat me" signaling proteins recognized by specialized cells of the immune system, University of California, Irvine molecular biologists and their colleagues ...

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