Ever since the decoding of the human genome in 2003, genetic research has been focused heavily on understanding genes so that they could be read like tea leaves to predict an individual's future and, perhaps, help them stave ...
Sep 17, 2018
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New research from Indiana University has identified "hotspots" in DNA where the risk for genetic mutations is significantly elevated.
Jul 30, 2018
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Researchers at the University of Oxford have discovered that a cellular mechanism preferentially protects plant genes from the damaging effects of mutation.
Jan 5, 2018
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In an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called 'mismatch repair' genetic defects, scientists at Johns Hopkins Medicine and its Bloomberg~Kimmel Institute ...
Jun 9, 2017
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Earlier this week, for the first time, a drug was FDA-approved for cancer based on disease genetics rather than type.
May 26, 2017
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In a report of a proof-of-principle study of patients with colon and other cancers for whom standard therapies failed, researchers at the Johns Hopkins Kimmel Cancer Center say that mistakes in so-called mismatch repair genes, ...
May 29, 2015
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A study that examined 17 million mutations in the genomes of 650 cancer patients concludes that large differences in mutation rates across the human genome are caused by the DNA repair machinery.
Feb 23, 2015
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A new study involving researchers at The University of Nottingham has revealed how children with an aggressive cancer predisposition syndrome experience a never before seen flood of mutations in their disease in just six ...
Feb 3, 2015
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When RNA component units called ribonucleotides become embedded in genomic DNA, which contains the complete genetic data for an organism, they can cause problems for cells. It is known that ribonucleotides in DNA can potentially ...
Dec 4, 2011
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In an editorial, in Oncoscience titled "Therapeutic opportunities for hypermutated urothelial carcinomas beyond immunotherapy," researcher Ioannis A. Voutsadakis from Sault Area Hospital and Northern Ontario School of Medicine ...
May 13, 2024
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