Oncology & Cancer

Gene fusion shifts cell activity into high gear, causing some cancer

The fusion of two adjacent genes can cause cancer by kicking mitochondria into overdrive and increasing the amount of fuel available for rampant cell growth, researchers at Columbia University Medical Center (CUMC) have discovered. ...

Endocrinology & Metabolism

Revealing the secrets of cell competition

Cellular competition is a crucial quality control process that ensures that the development of an organism relies on healthy cells. Researchers revealed the secrets underlying cell competition and what features can pre-determine ...

Medications

Study sheds light on diabetes drug for prostate cancer

In the years since a 2005 study found that diabetes patients taking metformin had lower rates of cancer, oncologists have been excited by the prospect of using the inexpensive, safe, and widely used diabetes drug to prevent ...

Oncology & Cancer

Targeting telomerase as therapeutic strategy for melanoma

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar ...

Genetics

Mitochondria adopt a crosswise pathway for decoding their genome

Mitochondria, true energy power plants of cells, are able to release the energy contained in food by means of the oxygen which we inhale. These intracellular organelles possess their own DNA, and proteins derived from these ...

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