Medical research

How cells keep gene silencing in check

Long considered 'junk," non-coding RNAs have emerged as important regulators of diverse cellular processes, including the silencing of genes. Working in yeast, researchers from the Bühler group have identified more than ...

Oncology & Cancer

Using math to kill cancer cells

Here's a good reason to pay attention in math class. Nature Communications has published a paper from Ottawa researchers today, outlining how advanced mathematical modelling can be used in the fight against cancer. The technique ...

Oncology & Cancer

Impact of epigenetics on the clinical management of cancer patients

In the early 1980s, the first changes in DNA related to a chemical modification called methylation were discovered, followed by the discovery in the mid-1990s of the first tumor suppressor genes inactivated by these modifications ...

Genetics

Decoding the language of epigenetic modifications

Epigenetic changes play important roles in cancer, metabolic and aging-related diseases, but also during loss of resilience as they cause the genetic material to be incorrectly interpreted in affected cells. A major study ...

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