Medical research

Regulating single protein prompts fibroblasts to become neurons

Repression of a single protein in ordinary fibroblasts is sufficient to directly convert the cells – abundantly found in connective tissues – into functional neurons. The findings, which could have far-reaching implications ...

Arthritis & Rheumatism

Scientists home in on cause of osteoarthritis pain

Researchers at Rush University Medical Center, in collaboration with researchers at Northwestern University, have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could ...

Diseases, Conditions, Syndromes

A urine test for Kawasaki disease

A set of proteins detected in urine by researchers at Boston Children's Hospital may prove to be the first biomarkers for Kawasaki disease, an uncommon but increasingly prevalent disease which causes inflammation of blood ...

Oncology & Cancer

Cancer stem cells isolated from kidney tumors

Scientists have isolated cancer stem cells that lead to the growth of Wilms' tumours, a type of cancer typically found in the kidneys of young children. The researchers have used these cancer stem cells to test a new therapeutic ...

Genetics

One gene predicts rapid ALS progression 80 percent of the time

(Medical Xpress)—The debilitating symptoms of amyotrophic lateral sclerosis, or ALS, appear to be increased by a lack of inflammation-reducing T cells, report scientists from the Methodist Neurological Institute in an upcoming ...

Medical research

Metabolic biomarkers for preventive molecular medicine

A team of scientists from the Spanish National Cancer Research Centre, led by its director, María Blasco, together with Jose M. Mato, the director of the Center for Cooperative Research in Biosciences, has shown that the ...

Alzheimer's disease & dementia

Molecular knock-out alleviates Alzheimer's symptoms in mice

Researchers at the German Center for Neurodegenerative Diseases (DZNE) and the University Medical Center Göttingen (UMG) have identified an enzyme as a possible target for the treatment of Alzheimer's disease. The protein ...

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