Medical research

New mouse model for hepatitis C

Hepatitis C affects about three million people in the U.S. and is a leading cause of chronic liver disease, so creating a vaccine and new treatments is an important public health goal. Most research to date has been done ...

Genetics

The naked mole-rat's secret to staying cancer free

A team of researchers from the University of Rochester (NY) and the University of Haifa discovered the naked mole rat's unique mechanism to staying cancer free- a super sugar called high-molecular-mass Hyaluronan (HMM-HA). ...

Oncology & Cancer

Boosting the immune response against cancer

T cells are usually good at eliminating diseased cells, but they seem to fail when it comes to tumor cells. In JCI Insight, MDC teams led by Armin Rehm and Uta Höpken describe what inhibits this immune function, and how ...

Immunology

Transporter's role in gut barrier linked to intestinal dysfunction

The cotransporter NKCC1 moves sodium, potassium and chloride ions across the cell membrane of many cell types, including intestinal epithelial cells. Two patients with mutations in NKCC1 suffered from severe intestinal dysfunction ...

Oncology & Cancer

Researchers identify mechanism that makes breast cancer invasive

A new study has identified a key mechanism that causes breast cancer to spread. The research, published by Cell Press on March 30th in the journal Molecular Cell, enhances our knowledge about the signals that drive cancer ...

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