Medical research
New mechanism for antibiotic tolerance found
(Medical Xpress)—Many antibiotics can lose their ability to kill bacteria – Duke University bioengineers believe they can explain one of the reasons why.
Oct 19, 2012
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Page 23 - News tagged with molecular modelling
Medical research
Protein could be key for drugs that promote bone growth
Georgia Health Sciences University researchers have developed a mouse that errs on the side of making bone rather than fat, which could eventually lead to better drugs to treat inflammatory diseases such as rheumatoid arthritis.
Oct 15, 2012
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Medical research
Novel mechanisms underlying major childhood neuromuscular disease identified
A study by scientists from the Motor Neuron Center at Columbia University Medical Center (CUMC) suggests that spinal muscular atrophy (SMA), a genetic neuromuscular disease in infants and children, results primarily from ...
Oct 11, 2012
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Inflammatory disorders
Researchers determine how inflammatory cells function, setting stage for future remedies
A research team led by investigators at New York University and NYU School of Medicine has determined how cells that cause inflammatory ailments, such as Crohn's disease, multiple sclerosis, and arthritis, differentiate from ...
Sep 26, 2012
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Genetics
Low oxygen levels may decrease life-saving protein in spinal muscular atrophy
Investigators at Nationwide Children's Hospital may have discovered a biological explanation for why low levels of oxygen advance spinal muscular atrophy (SMA) symptoms and why breathing treatments help SMA patients live ...
Aug 21, 2012
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Neuroscience
Rejected drug may protect against toxic substance common to Alzheimer's and Parkinson's diseases
The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative ...
Aug 13, 2012
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Oncology & Cancer
Treating drug resistant cancer through targeted inhibition of sphingosine kinase
Scientists at Tulane University School of Medicine, led by Dr. James Antoon and Dr. Barbara Beckman, have characterized two drugs targeting sphingosine kinase (SK), an enzyme involved in cancer growth and metastasis. New ...
Aug 9, 2012
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Oncology & Cancer
Taking a hit or two
Cancer only arises if two or more genes are mutated. Learning which combinations of mutations cause cancer represents an extremely laborious endeavor. In the current issue of the journal Nature Methods Robert Eferl and colleagues ...
Aug 6, 2012
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Oncology & Cancer
Cell differentiation as a novel strategy for the treatment of an aggressive type of skin cancer
Skin squamous cell carcinoma (SCC) is a subtype of very aggressive skin cancers that usually develops in sunexposed body regions, but can also affect a large number of organs such as the bladder, esophagus, lungs etc. However, ...
Jul 9, 2012
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Oncology & Cancer
Scientists develop mouse model that could lead to new therapies for liver cancer
Researchers have created the first mouse model demonstrating the role of a cancer promoting gene, Astrocyte elevated gene-1 (AEG-1), in hepatocellular carcinoma, or liver cancer. The mouse model represents a critical step ...
Jul 6, 2012
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