Genetics

Exploring the role of lamin in normal aging

Since the discovery that mutations in the LMNA gene (which encodes the nuclear structure components lamin A and C) lead to Hutchinson-Gilford progeria syndrome (HGPS), people have speculated that lamins may have a role in ...

Oncology & Cancer

Boosting the immune response against cancer

T cells are usually good at eliminating diseased cells, but they seem to fail when it comes to tumor cells. In JCI Insight, MDC teams led by Armin Rehm and Uta Höpken describe what inhibits this immune function, and how ...

page 13 from 23